Frank McComb began his career in February 1983 when an aunt began teaching him piano at the family church. Though he did attend a school for the performing arts in the mid-80's, he found more recognition playing Cleveland nightclubs with seasoned musicians. By 1988, McComb was in high school fronting his own trio.
After graduating from Glenville High School in Cleveland, OH, McComb was asked to be in the band for Atlantic Records male R&B singing group The Rude Boys, protégés of Gerald Levert. He was soon promoted to musical director and toured with them through the early 90's. While touring, McComb met Jeff Townes of seminal rap duo DJ Jazzy Jeff & The Fresh Prince who invited him to record and tour with the group. Townes eventually convinced Frank to move to Philadelphia. Once settled, he was introduced to legendary songwriting duo Kenny Gamble and Leon Huff. McComb was eventually put on payroll as a musician for Gamble/Huff and moved down the street from their headquarters so that he could walk to work every day.